PREDATOR ENVIRONMENT DOES NOT PREDICT LIFE HISTORY IN THE MORPHOLOGICALLY CONSTRAINED FISH ALFARO CULTRATUS (CYPRINODONTIFORMES: POECILIIDAE)

Predator Environment Does Not Predict Life History in the Morphologically Constrained Fish Alfaro cultratus (Cyprinodontiformes: Poeciliidae)

Predation is known to have a significant effect on life history diversification in a variety of species.However, physical constraints of body shape and size can sometimes limit life history divergence.We test this idea in the Costa Rican livebearing fish Alfaro cultratus.Individuals in this species have a narrow body and keeled ventral sequal eclip

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Bacterial capsular polysaccharides with antibiofilm activity share common biophysical and electrokinetic properties

Abstract Bacterial biofilms are surface-attached communities that are difficult to eradicate due to a high tolerance to antimicrobial agents.The use of non-biocidal surface-active compounds to prevent the initial adhesion and aggregation of bacterial pathogens is a promising alternative to antibiotic treatments and several antibiofilm compounds hav

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Multiple autoimmune-associated variants confer decreased IL-2R signaling in CD4+ CD25(hi) T cells of type 1 diabetic and multiple sclerosis patients.

IL-2 receptor (IL-2R) signaling is essential for optimal stability and function of CD4(+)CD25(hi)FOXP3(+) regulatory T cells (Treg); a cell type that plays an integral role in maintaining tolerance.Thus, we hypothesized that decreased response to IL-2 may be a common phenotype of subjects who have autoimmune diseases associated with variants in the

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